Skip to content

Working to end PSC

We're here to help anyone affected by PSC and to drive PSC research towards a cure

PSC Support is the leading organisation for anyone affected by primary sclerosing cholangitis (PSC)

PSC is a rare, immune-mediated liver disease that can affect anyone, at any age. PSC is complex and current evidence suggests that people with a genetic makeup may be susceptible to some sort of (as yet unknown) environmental trigger, which causes their immune system to effectively 'attack' the bile ducts.

Looking for a London Marathon place?

Do you want to run in the Virgin Money VIRTUAL London Marathon? We have five places available in the virtual race scheduled for 03 October 2021. Apply now.

We're here for you

Patient stories

Stories written by you about living with PSC

Find clinical trials

Take part in cutting edge research to help find a cure for PSC

COVID-19 and PSC

Get the latest information for you and your doctors

Get support

You don't need to face PSC alone

Get the PSC Alert Card

Emergency cholangitis information

Our vision is to see a world without PSC


We provide patients and families with high-quality, accessible information and the support they need; we collaborate with healthcare providers to improve clinical care; we shape and fund critical research so that we can live in a world without PSC.

PSC News

Pregnancy in PSC and post-liver transplant

Updated Information: Pregnancy in PSC and post-liver transplant


Pregnancy in PSC and post-liver transplant Updated information We have a lot of young adults in our PSC community. We’re often asked whether PSC or having had a liver transplant should stop you starting a family. The answer is no, but you should talk to your PSC doctor or your transplant team beforehand in case a…

Vaccine and immunosuppressants web

COVID Vaccines and the Immune System


How do COVID vaccines affect people who are taking immunosuppressive medicines?

Jenny Fundraiser

Jenny is Fundraising for PSC Support Through her Business


Jenny is donating 10% of the purchase price of stationery, cards and craft kits to PSC Support until 07 March

NHSBT Liver Transplant Update - Feb 2021

NHSBT Liver Transplant Update for Patients (February 2021)


Important information for anyone on the liver transplant waiting list.


Exciting to hear that our grant for research on Treg cells in PSC has led to in vivo models for liver regeneration. Thank you @WeiYu_Lu and Naruhiro Kimura! @BirminghamLiver @EASLnews @AASLDtweets @AutoImmuneLiver @LiverForum @PSCPartnersCa #livertwitter

Liver Immunology@BirminghamLiver

We welcome @WeiYu_Lu and Naruhiro Kimura at todays' research-in-progress meeting: exciting in vivo models for liver regeneration and PSC funded by @PSCPartners

We're often asked whether #PSC or having had a #LiverTransplant should stop you starting a family. The answer is no!

We've put together new and comprehensive information about this topic, with the help of @MichaelHenegha8 and @MussaratRahim.

@louistheroux @BBCTwo A Louis Theroux documentary series on living with a rare disease that has no/limited treatments, for example Primary Sclerosing Cholangitis (PSC) and organ transplantation would not only be very interesting but help raise much needed awareness 👌🏻 #leatsbeatpsc @PSCSupportUK 👍🏻