The Birmingham PSC Clinical Programme - a Centre of Excellence

Based between the Queen Elizabeth Hospital, Birmingham and the Centre for Liver Research, University of Birmingham, the Birmingham PSC programme is one of the largest and most active in the world.  It looks after patients from all over the country, striving to deliver a patient centred, disease focussed, clinical programme, as advanced as any in the world.

Autoimmune liver diseases are a high priority for the QE Liver Unit, and the autoimmune liver disease service is lead by Dr Gideon Hirschfield.  Beyond a comprehensive research and trials programme, it consists fundamentally of three clinics per week:

  • PBC (Monday afternoon)
  • PSC (Wednesday afternoon)
  • AIH (Thursday morning)

The Wednesday PM clinic currently sees between 20-40 patients a week, consisting of an equal mix of pre- and post-transplant PSC patients.  The clinic lead is Dr James Ferguson, who also leads for Transition services in liver disease, as well as developing novel IT solutions for delivery of healthcare.  Dr Hirschfield, Dr Thompson, Dr Trivedi and Dr Corrigan currently work with James to share the clinical work load.  Within clinic there is a dedicated Fibroscan service, appropriate nurse support, and emerging opportunities for virtual clinics as well as access to hospital records for patients (MyHealth).  Close contact is made with PSC Support, and Birmingham hosts a successful annual patient day annually for PSC Support.


The autoimmune liver disease programme in Birmingham is very focused on translating basic science discoveries into new treatments for patients, and PSC clinical trial activity in Birmingham is very active.  Dr Hirschfield is happy to be contacted regarding the various clinical trials presently recruiting.  Within the Liver Biomedical Research Unit, lead by Prof Adams (a clinician scientist spearheading research into new therapies for patients with liver disease, as well as being the new Head of the College of Medicine and Dentistry at the University) there is a strong focus on new scientific discovery for the benefit of patients with liver disease.

Beyond the PSC programme itself, is the ready support offered by the wider QE Liver Unit, one of Europe’s largest all inclusive hepatology/liver transplant programmes.  With on average nearly four transplants per week in Birmingham, the whole team is highly focused on liver medicine, and consists of highly skilled surgeons, anaesthetists, physicians, nurses, pharmacists, pathologists, radiologists, dieticians, psychologists, managers and administrative staff.

See also: Phase II Clinical Trials

Updated 27 April 2015

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