Appraisal Criteria in Grant Applications

How will PSC Support appraise my grant application?

Grants are awarded on the basis of scientific merit and clear relevance to PSC Support’s Research Strategy. The Research Advisory Panel scores the application according to the following criteria:

Scientific Appraisal Criteria Guide

  1. Relevance of idea or proposal
    Refer to PSC Support’s Research Strategy. How does the proposal relate to our charity aims and priorities?
  2. Patient-Relevant outcomes
    Is the proposal testing patient-centred outcomes eg quality of life, survival, itching, pain, fatigue, group identification (eg high risk cancer, high risk PSC)/ making progress towards using patient-centred outcomes in the future?
  3. Originality
    Does the proposal address an important and valid research question? Also refer to PSC Patients’ Unanswered Questions.
  4. Realistic costing and value for money
    Is the budget realistic, value for money and costs justified?
  5. Relationship to and the volume of research already available in the field
    Has the proposal considered relevant PSC literature and developments?
  6. Scientific quality or methodology
    What is the quality of the experimental design or method?
  7. Expertise of researchers
    Does the research team have the right expertise for the proposed research?
  8. Use of animals in research
    Funding applications involving the use of animals must comply with the law and support the principle of the 3Rs to refine, reduce and replace the use of animals in research. PSC Support supports the AMRC Statement on Animal Research. Our expectations for responsible use of animals are set out in the document Responsibility in the use of animals in bioscience research.

Lay Appraisal Criteria Guide

The research grant applications are considered by lay reviewers (usually patients) as well as by scientific experts. Lay reviewers will appraise the application based on the importance of this research and the potential difference this could make to people affected by PSC, and the progress this research could make towards answering and ‘unanswered research question’.

Patients are involved in appraising research applications because PSC Support places great value on the patient voice. For this reason, there is no word limit on the lay summary section of the application form. While patients might not fully comprehend the technical and scientific aspects of the project, they are interested in what the project entails and we 'get' that it takes more words when you explain something technical!

  1. Importance of this research to people with PSC
    Do you think this research is important to people with PSC?
  2. Likelihood that this research will make a difference to people with PSC
    Do you think the outcomes of this research will make a difference to people with PSC?
  3. Makes progress towards an ‘unanswered question’ in PSC
    Do you think this research is answering one of our ‘unanswered questions’ or making progress to answering one?

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