Working to end PSC

We're here to help anyone affected by PSC and to drive PSC research towards a cure

PSC Support is the leading UK-based organisation for anyone affected by primary sclerosing cholangitis (PSC). We’re here to help, whether you are a patient, family member, healthcare provider or researcher.


PSC is a rare, immune-mediated liver disease that can affect anyone, at any age. PSC is complex and current evidence suggests that people with a genetic makeup may be susceptible to some sort of (as yet unknown) environmental trigger, which causes their immune system to effectively 'attack' the bile ducts.


PSC Support is working to improve the lives of people affected by PSC by providing support and information, campaigning to improve the care we receive, and funding critical research to find effective PSC treatments.

font page liver transplant

Liver Transplant for PSC

Everything you need to know from transplant assessment to coming home after your liver transplant.

front page leaflets

Download important PSC information

Leaflets on PSC and on bacterial cholangitis


Just diagnosed?

Ten tips on handling your diagnosis from people living with PSC

World without psc

Imagine a world without PSC?

That's what we're doing


PSC News

PSC Support – A Year in Review 2019

December 23, 2019

It’s been quite a year for PSC Support, we are proud to share a few highlights from 2019!

Join our focus group

Calling Liver Transplant Patients!

December 17, 2019

If you have had a liver transplant, would you like to join our focus group to help a researcher improve outcomes for liver transplant patients?


Registration Open for Newport 2020 Information Day

December 14, 2019

Register for our joint PSC Support and AIH Support Patient Information Day in Newport, Wales.

Patient Survey on Acceptability of Treatments in AIH

December 11, 2019

If you have AIH, please take a few moments to help researchers and doctors improve treatment.

#WillSmith 'vlogged' his first experience of having a colonoscopy!
👀 👉

Having a colonoscopy is something most PSC patients are very familiar with. Who can relate to the effects of the sedation? 🙈

Read more about PSC and IBD -

Are you thinking of fundraising for PSC Support in 2020 to help us improve the lives of people affected by PSC?

Download your free fundraising pack which is full of useful tips, resources and inspiration to kickstart your fundraising ideas!

Have you seen @NHSOrganDonor's advert on TV to highlight the upcoming opt-out system?

PSC is one of the leading causes of liver transplant in the UK. We welcome the new law & urge you to share your organ donation wishes.

More about organ donation & PSC -

We've teamed up with @AIHorgUK for our upcoming Information Day in Wales.

You can choose to attend talks on PSC or AIH from some of the UK's experts. There will also be a short session for people living with both PSC & AIH.

Register for your FREE place-