Working to end PSC

We're here to help anyone affected by PSC and to drive PSC research towards a cure

PSC Support is the leading UK-based organisation for anyone affected by primary sclerosing cholangitis (PSC). We’re here to help, whether you are a patient, family member, healthcare provider or researcher.


PSC is a rare, immune-mediated liver disease that can affect anyone, at any age. PSC is complex and current evidence suggests that people with a genetic makeup may be susceptible to some sort of (as yet unknown) environmental trigger, which causes their immune system to effectively 'attack' the bile ducts.


PSC Support is working to improve the lives of people affected by PSC by providing support and information, campaigning to improve the care we receive, and funding critical research to find effective PSC treatments.

font page liver transplant

Liver Transplant for PSC

Everything you need to know from transplant assessment to coming home after your liver transplant.

front page leaflets

Download important PSC information

Leaflets on PSC and on bacterial cholangitis


Just diagnosed?

Ten tips on handling your diagnosis from people living with PSC

World without psc

Imagine a world without PSC?

That's what we're doing


PSC News

PSC Support Christmas

Donate to PSC Support This Christmas

November 15, 2019

Let your friends and family know you have made a donation to PSC Support instead of buying Christmas cards this year.

Tests and Procedures PSC Support

Tests And Procedures For PSC

November 13, 2019

Tests and procedures are an important aspect of PSC care, but it’s not easy to know what the tests mean and why they are helpful for managing our condition. This video explains what tests are used and when.

UKPSC logo

UK-PSC Guidelines Launched

November 7, 2019

The UK-PSC Guidelines for managing PSC were officially launched last week. What are the main recommendations and what do they mean for your care?

Nathan after transplant

Letter to My Organ Donor Family

November 2, 2019

Nathan talks about his transplant for PSC and shares the letter he wrote to the family of his organ donor

📣Do not miss the date!!! Next week deadline for abstract submition!!!! Nov 26th! Travel bursaries for selected abstracts presented by YIs. All types of Liver Cancers included in the program. @EASLedu @CcaEns @CharityAMMF @curecc @CCA_Alliance

Really chuffed - my 2020 Calendar in aid of @PSCSupportUK is just about to hit the £600 mark and 100% of the proceeds go to the charity.

Last year's raised £687. Can you help beat that amount? That's another eleven A4s, or just seven A3s!

Not sending Christmas cards this year?

If you've donated to PSC Support in lieu of sending cards this year, share our image with your friends and family to let them know. Thank you!

#LetsBeatPSC #Christmas #ChristmasGiving 🎄