Working to end PSC

We're here to help anyone affected by PSC and to drive PSC research towards a cure

PSC Support is the leading UK-based organisation for anyone affected by primary sclerosing cholangitis (PSC). We’re here to help, whether you are a patient, family member, healthcare provider or researcher.


PSC is a rare, immune-mediated liver disease that can affect anyone, at any age. PSC is complex and current evidence suggests that people with a genetic makeup may be susceptible to some sort of (as yet unknown) environmental trigger, which causes their immune system to effectively 'attack' the bile ducts.


PSC Support is working to improve the lives of people affected by PSC by providing support and information, campaigning to improve the care we receive, and funding critical research to find effective PSC treatments.

font page liver transplant

Liver Transplant for PSC

Everything you need to know from transplant assessment to coming home after your liver transplant.

front page leaflets

Download important PSC information

Leaflets on PSC and on bacterial cholangitis

Just diagnosed?

Ten tips on handling your diagnosis from people living with PSC

World without psc

Imagine a world without PSC?

That's what we're doing


PSC News

Livernorth Jess Dyson talk

Dr Jess Dyson: What’s New in Autoimmune Liver Disease

September 14, 2019

Consultant hepatologist Dr Jess Dyson, member of PSC Support’s Expert Panel, talks about her research interest in why people get autoimmune liver diseases at a recent LIVErNORTH patient meeting, focusing on possible environmental factors.

FMT Vancomycin PSC Support Survey

Faecal Microbiota Transplant and Vancomycin for PSC

September 13, 2019

Take two minutes to do our quick poll about the best way to conduct a faecal microbiota transplant and vancomycin study. THANK YOU!

Your liver transplant

Supercool Livers

September 13, 2019

A new method for liver transplants from Harvard scientists.

MRCP+ Study Perspectum

Testing the Utility of MRCP+

September 12, 2019

New study is looking at a new technology that could aid PSC diagnosis and how progression of disease is measured.

Congratulations to @DocKateLynch on her award for best poster at #BASL2019. Proud that this study is part-funded by PSC patients. @PSCSupportUK

'She won't recruit with that invasive procedure,' they said.

Dr Kate Lynch wanted to take FNA samples from patients for this study.

She *did* recruit, it was safe in PSC, and 88% said they'd have another FNA.

#ListenToPatients 🙂 #BASL2019 @DocKateLynch @EmmaCulver6

#BASL2019 Come and visit us at our stand in the exhibition area for information about how we are helping PSC patients. @maxceline_ @F8Martine

Great to be part of the discussion this afternoon at #basl2019. Exciting to think about the potential benefits of MP for patients and current evidence looks good but lots more to learn!