Working to end PSC

We're here to help anyone affected by PSC and to drive PSC research towards a cure

PSC Support is the leading UK-based organisation for anyone affected by primary sclerosing cholangitis (PSC). We’re here to help, whether you are a patient, family member, healthcare provider or researcher.


PSC is a rare, immune-mediated liver disease that can affect anyone, at any age. PSC is complex and current evidence suggests that people with a genetic makeup may be susceptible to some sort of (as yet unknown) environmental trigger, which causes their immune system to effectively 'attack' the bile ducts.


PSC Support is working to improve the lives of people affected by PSC by providing support and information, campaigning to improve the care we receive, and funding critical research to find effective PSC treatments.


Get a PSC Alert Card

PSC Alert Card

Carry an Alert Card for bacterial cholangitis

Find Clinical Trials for PSC

Clinical Trials

Find clinical trials and research studies for PSC

World without psc

Imagine a world without PSC?

That's what we're doing

Your Medical Care

Your Medical Care

What to expect from your doctor

Fundraise for PSC Support


Start fundraising for PSC Support


PSC News

Logo ERN-rareliver

European Healthcare Survey

April 7, 2020

Please take 5 minutes to help improve healthcare for rare liver disease across Europe.

Martine Walmsley

Opinion: We’re All a Little Vulnerable Right Now

April 5, 2020

We’re all a little vulnerable right now, but we’re in this together and will get through it.

EASL Position Statement on COVID-1 (1)

Caring for People with Liver Disease During COVID-19

April 3, 2020

Patients with advanced liver disease and transplant recipients require specific care during COVID-19



March 26, 2020

Join the nation to #clapforourcarers at 8pm Thursday 26th March 2020.

Did you know you can raise money for PSC Support as you shop online? Last year, our amazing supporters raised £207 via The Giving Machine.

Visit their website to sign up 👉

We're so grateful to all of our supporters during this challenging time 🙌

I've been reflecting on the surreal events of the past couple of weeks, and how they're impacting our PSC community, particularly here in the UK. #VulnerableButOK