Working to end PSC

We're here to help anyone affected by PSC and to drive PSC research towards a cure

PSC Support is the leading UK-based organisation for anyone affected by primary sclerosing cholangitis (PSC). We’re here to help, whether you are a patient, family member, healthcare provider or researcher.


PSC is a rare, immune-mediated liver disease that can affect anyone, at any age. PSC is complex and current evidence suggests that people with a genetic makeup may be susceptible to some sort of (as yet unknown) environmental trigger, which causes their immune system to effectively 'attack' the bile ducts.


PSC Support is working to improve the lives of people affected by PSC by providing support and information, campaigning to improve the care we receive, and funding critical research to find effective PSC treatments.

font page liver transplant

Liver Transplant for PSC

Everything you need to know from transplant assessment to coming home after your liver transplant.

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Download important PSC information

Leaflets on PSC and on bacterial cholangitis


Just diagnosed?

Ten tips on handling your diagnosis from people living with PSC

World without psc

Imagine a world without PSC?

That's what we're doing


PSC News

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UK-PSC Guidelines Launched

November 7, 2019

The UK-PSC Guidelines for managing PSC were officially launched last week. What are the main recommendations and what do they mean for your care?

Nathan after transplant

Letter to My Organ Donor Family

November 2, 2019

Nathan talks about his transplant for PSC and shares the letter he wrote to the family of his organ donor

PSC Support Calendar 2020

Buy PSC Support Calendars

October 31, 2019

PSC Support calendars are back! 2020calendars are now available to buy and proceeds will be donated to PSC Support.

PSC Support Christmas Cards All

Buy Christmas Cards

October 31, 2019

Jenny’s beautiful handmade Christmas Cards are ready to buy!

Great numbers. Still have concerns about hepatotoxicity rates but encouraging data. QoL in #PBC and #PSC hugely important. @PBCFoundation @PSCSupportUK @PSCPartners

Hearing at #IPSCSG plans to use proteomics and metabolomics to diagnose cholangiocarcinoma early in PSC. Important efforts. Fits alongside ongoing efforts to diagnose colorectal cancer early.

Interim results from FICUS study of the IPSCSG @PSCSupportUK @PSCPartners. Baseline fibroscan is an independent predictor of mortality without #transplant. @AASLDtweets