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Working to end PSC

We're here to help anyone affected by PSC and to drive PSC research towards a cure

PSC Support is the leading organisation for anyone affected by primary sclerosing cholangitis (PSC)

PSC is a rare, immune-mediated liver disease that can affect anyone, at any age. PSC is complex and current evidence suggests that people with a genetic makeup may be susceptible to some sort of (as yet unknown) environmental trigger, which causes their immune system to effectively 'attack' the bile ducts.

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Patient stories

Stories written by you about living with PSC

Find clinical trials

Take part in cutting edge research to help find a cure for PSC

COVID-19 and PSC

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Emergency cholangitis information

Our vision is to see a world without PSC


We provide patients and families with high-quality, accessible information and the support they need; we collaborate with healthcare providers to improve clinical care; we shape and fund critical research so that we can live in a world without PSC.

PSC News

Christmas Cards

Send eGreetings this Christmas


Let your friends and family know that you are donating to PSC Support this year instead of posting out cards.

Ask the Expert with UK PSC

PSC Research in the UK and Beyond


Ask the Expert with UK-PSC: PSC Research in the UK and Beyond

EASL International Liver Congress

Research Report on PSC from EASL International Liver Congress


Our Report on PSC research from the International Liver Congress 2020

Clinical Trials Guide web 1

Free Clinical Trials Guide for Patients


Download our new FREE guide to taking part in clinical trials.

I'm 75% of the way to my fundraising target for PSC - Support. Massive thanks to everyone who has helped – you can follow my progress here: #JustGiving

@tomhemmingk @hov_jer Every time I see a paper like this my mind flips to @PSCPartners @PSCSupportUK and what is happening in our patient's bowel and biliary tree.

Gut microbiota–specific IgA B cells traffic to the CNS in active multiple sclerosis

Clinical trials for PSC are here. We want PSC patients to be informed about taking part, so we've put together this 24-page guide, based on patients' questions. Considering PSC patients for CTs should become the norm, not the exception. #LetsBeatPSC