If you are at all concerned about your health and suspect that the issue is related to PSC, let your doctor know.
It’s important to contact your doctor in certain situations, including:
Suddenly feeling generally unwell, fluey and itchy
This could be a bile duct infection (bacterial cholangitis).
If you develop jaundice all of a sudden (skin getting a yellowish tinge, whites of eyes becoming yellow), contact your PSC doctor immediately so he or she can make the appropriate assessment and investigations.
Sudden pain or itch
Sometimes sudden pain is associated with an infection in the bile ducts which may respond well to antibiotics (see bacterial cholangitis).
Itch that is not resolving even with medicine
Let your doctor know. There are several different medicines for itch that work differently, and another type might be more suitable for you.
An unexplained cough (when you have advanced PSC)
Let your doctor know. This could be an indication of varices.
Sudden unintended weight loss
Let your doctor know. There are a number of causes of unintended weight loss which your doctor will investigate, and you may benefit from professional dietary advice.
Nausea shortly after eating
Let your doctor know if this persists. This could be related to your IBD or be related to the jobs your bile is supposed to do causing steatorrhoea. This may be manageable with expert dietary support.
Signs of a blood clot
Sudden onset of swollen calf or thigh. Sudden onset of shortness of breath or pain in the ribs that is worse when breathing in.
There is in an increased risk of clots in the veins of the legs (deep vein thromboembolism) and also in the lungs (pulmonary embolism) in patients with PSC. If any of these ever develop please seek urgent medical advice and treatment.
Remember, this list is not exhaustive and if you are unsure, please check with your doctor.