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Vaccines for COVID-19

Updated 14th January 2021

Vaccines in use in the United Kingdom

The first vaccine to help protect us from COVID-19 was approved on 02 December 2020. Some people with PSC have been prioritised to receive the vaccine early.

Pharmaceutical companies have been running clinical trials to evaluate the safety and efficacy (effectiveness) of COVID-19 vaccine across the world. They have been able to gather the necessary data in record time by adopting special trial designs.

Next, the body that regulates medicines, the MHRA, reviews information from these trials to decide if they are safe and effective enough to be used. The MHRA evaluates the data rigorously for quality, safety and effectiveness to reach an independent, scientifically robust opinion. The data must include results from lab and clinical trials in humans; manufacturing and quality controls, product sampling, and testing of the final product.

The MHRA is globally recognised for requiring the highest standards of safety, quality and effectiveness for any vaccine.

Vaccine Q&A (NHSBT)

Published 14 Jan 2021: Questions and answers for patients and clinicians on the COVID-19 vaccines, from NHSBT, the body that oversees transplantation in the UK.

COVID-19 Vaccine – Q&As for Clinicians and People who have had a transplant, are waiting for one or are a living donor

Which vaccines have been approved by the MHRA?

The following vaccines have been given MHRA regulatory approval:

  1. 02 December 2020 - Pfizer/BioNTech vaccine.
    See Regulatory approval of Pfizer/BioNTech vaccine for COVID-19
  2. 30 December 2020 - Oxford/AstraZeneca vaccine.
    See Regulatory approval of COVID-19 Vaccine AstraZeneca
    See 'More people are eligible to receive the COVID-19 vaccine.'
  3. 08 January 2021 - Moderna vaccine.
    See Moderna vaccine becomes third COVID-19 vaccine approved by UK regulator
    See Regulatory approval of COVID-19 Vaccine Moderna

Position Statements

Guidance from professional societies about having the vaccine.

Ask the Expert Video

18 Dec 2020: Live Q&A

We held an excellent live Q&A with Dr Palak Trivedi and AIH Support on 18th December 2020 about COVID vaccines and autoimmune liver disease:


Updated 31 December 2020

More information about the vaccines

On 25 November 2020, Professor Tim Spector, ZOE COVID Symptom Study lead, spoke to leading immunologist, Professor Peter Openshaw from Imperial College London, to answer questions about COVID vaccines.

Liver transplants

Everything you need to know about having a liver transplant

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